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Image Search Results
Journal: Genes
Article Title: Integrative Transcriptomic Analysis Identify Potential m6A Pathway-Related Drugs That Inhibit Cancer Cell Proliferation
doi: 10.3390/genes13112011
Figure Lengend Snippet: Effect of AZ628 on human breast cancer cell line MCF7. ( A , B ) The proliferation of human breast cancer cell line MCF7 was significantly inhibited by AZ628 treatment. The results from the cell count assay ( A ) and the MTT assay ( B ) are shown. Data represented the mean ± SEM from five independent experiments, t -test, ** p < 0.01. Some SEM values in the drug-treated experimental group that are too small to be shown are specified here: ( A ) 24 h. 0.021; 48 h, 0.013; 72 h, 0.001; 96 h, 0.001; ( B ) 24 h. 0.035; 48 h, 0.038; 72 h, 0.047; 96 h, 0.094. ( C , D ) The protein expression of METTL3 in the MCF7 cell line was not significantly affected by drug treatment, t -test, none significance (ns). The summary of Western blot grey values as the mean ± SEM from three independent experiments ( C ) and the representative Western blot result ( D ) are shown. ( E ) The RNA m6A modification level in the MCF7 cell line was significantly decreased after AZ628 treatment. Data represented the mean ± SEM from five independent experiments, t -test, * p < 0.05. ( F , G ) Representative images of treated and control cells observed under an inverted 10× microscopy.
Article Snippet: The
Techniques: Cell Counting, MTT Assay, Expressing, Western Blot, Modification, Control, Microscopy